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Stone Analysis [FT-IR]
| GC Labs code | Z018 | Test Field | Endocrinology |
|---|---|---|---|
| Compulsory forms | |||
Information
| Test method | IR (Infrared absorption spectrometry) |
|---|---|
| Specimen (mL) | Stone 1.0 mg |
| Specimen storage | Ambient, Sealed |
| Specimen stability | Ambient (3 months) |
| Test schedule | Mon-Fri |
| Analytical time (day) | 1 |
| Reference range/Unit | [Stone] See comments in the report |
|---|---|
| Clinical Significance | The composition of urinary stones may vary from a simple crystal to a complex mixture containing several different species of crystals. The composition of the nidus (center) may be entirely different from that of the peripheral layers. Eighty percent of patients with kidney stones have a history of recurrent stone formation. Knowledge of stone composition can be useful to guide therapy of patients with recurrent stone formation. Treatment of urinary calculi is complex.(1) In an overly simplified format, the following patterns are often treated as follows: -Hyperuricuria and predominately uric acid stones: Alkalinize urine to increase uric acid solubility -Hypercalciuria and predominately hydroxyapatite stones: Acidify urine to increase calcium solubility However, treatment also depends on urine pH and urine phosphate, sulfate, oxalate, and citrate concentrations. -Hyperoxaluria and calcium oxalate stones: Increase daily fluid intake and consider reduction of daily calcium However, daily requirements for calcium to maintain good bone formation complicate the treatment. -Magnesium ammonium phosphate stones (struvite): Investigate and treat urinary tract infection. |
| Remark | ① Sealing is required (Avoid damaging container) ② Urine and tissue specimens are unsuitable |