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NK cell activity test

GC Labs code	L461	Test Field	Immunology
Compulsory forms

GC Labs code

L461

Test Field

Immunology

Compulsory forms

Information

Test method	ELISA (Enzyme linked immunosorbent assay)
Specimen (mL)	P 0.5 (exclusive container)
Specimen storage	Frozen
Specimen stability	Frozen (1 month)
Test schedule	Mon-Fri
Analytical time (day)	1

Test method

ELISA (Enzyme linked immunosorbent assay)

Specimen (mL)

P 0.5 (exclusive container)

Specimen storage

Frozen

Specimen stability

Frozen (1 month)

Test schedule

Mon-Fri

Analytical time (day)

Reference range/Unit	[Plasma] See comments in the report
Clinical Significance	Natural killer (NK) cells are derived from pluripotent hematopoietic stem cell precursors but develop independently of the thymus. They comprise a key lymphocyte subset (approximately 10%-15% of peripheral blood mononuclear cells) and are a constituent of the innate immune system since these cells do not rearrange their germline DNA to obtain specificity. NK cells serve an important role in host defense against viral infections, as well as tumor surveillance. They are also a component of the adaptive immune response through cytokine production. NK cell functions are governed by a balance between activating receptors and inhibitory receptors.
Remark	[Specimen handling method] ① Store it in an incubator within 30 minutes after specimen collection ② Collect the supernatant after 20~24 hours of incubation

Reference range/Unit

 [Plasma]
See comments in the report

Clinical Significance

Natural killer (NK) cells are derived from pluripotent hematopoietic stem cell precursors but develop independently of the thymus. They comprise a key lymphocyte subset (approximately 10%-15% of peripheral blood mononuclear cells) and are a constituent of the innate immune system since these cells do not rearrange their germline DNA to obtain specificity. NK cells serve an important role in host defense against viral infections, as well as tumor surveillance. They are also a component of the adaptive immune response through cytokine production. NK cell functions are governed by a balance between activating receptors and inhibitory receptors.

Remark

[Specimen handling method]
① Store it in an incubator within 30 minutes after specimen collection
② Collect the supernatant after 20~24 hours of incubation