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Human papillomavirus genotyping [Multiplex real-time PCR]

GC Labs code	D126	Test Field	Infectious disease
Compulsory forms

GC Labs code

D126

Test Field

Infectious disease

Compulsory forms

Information

Test method	Real-time PCR
Specimen (mL)	Cervical swab Cervical liquid cell
Specimen storage	Refrigerated
Specimen stability	Refrigerated (90 days)
Test schedule	Mon-Sat
Analytical time (day)	1

Test method

Real-time PCR

Specimen (mL)

Cervical swab
Cervical liquid cell

Specimen storage

Refrigerated

Specimen stability

Refrigerated (90 days)

Test schedule

Mon-Sat

Analytical time (day)

Reference range/Unit	[Cervical liquid cell] See comments in the report [Cervical swab] See comments in the report
Clinical Significance	Human papillomavirus (HPV) infections with low-risk genotypes (6, 11) can cause benign hyperplasia such as condylomas and papillomas. Persistent infections with high-risk genotypes (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, and 82) are associated with cervical, vaginal, vulvar, and head and neck malignancies. Patients with HPV-related oropharyngeal squamous cell carcinoma (OPSCC) have shown better disease-specific survival and overall survival when compared to HPV-negative cases of OPSCC.
Remark

Reference range/Unit

 [Cervical liquid cell]
See comments in the report

 [Cervical swab]
See comments in the report

Clinical Significance

Human papillomavirus (HPV) infections with low-risk genotypes (6, 11) can cause benign hyperplasia such as condylomas and papillomas. Persistent infections with high-risk genotypes (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, and 82) are associated with cervical, vaginal, vulvar, and head and neck malignancies. Patients with HPV-related oropharyngeal squamous cell carcinoma (OPSCC) have shown better disease-specific survival and overall survival when compared to HPV-negative cases of OPSCC.

Remark