|
Clinical Significance
|
This test measures total IgE and simultaneously detects 160 respiratory and food allergens that are commonly found in Koreans, totaling 161 items.
Similar to ImmunoCAP, results are reported in classes 0 to 6. However, while ImmunoCAP is a quantitative test for individual allergens (indicating the class to which each quantitative value belongs), the MAST test is a semi-quantitative test, in which the results are determined based on the intensity of the color band.
The MAST test has the advantage of allowing simultaneous testing for multiple allergens, but its sensitivity and specificity are lower compared to ImmunoCAP. It is also prone to cross-reactivity between nearby allergens or allergens of the same type (e.g., citrus fruits, shellfish, fungi).
In particular, total IgE results from the MAST test show low correlation with those from ImmunoCAP and other quantitative tests, so caution is required in interpretation.
If the MAST test shows positive results, or if the clinical findings (e.g., patient history) do not match the MAST test results, confirmation using ImmunoCAP is recommended. |