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Clinical Significance
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This test is conducted for the diagnosis, prognosis assessment, and treatment decision-making of myelodysplastic syndromes (MDS). DNA is extracted from bone marrow and blood to analyze mutation information in genes related to the disease. It is capable of detecting SNV (single nucleotide variants) and small indels (insertions/deletions). The mutation detection sensitivity is approximately 5%, and it is particularly sensitive in detecting FLT3-ITD mutations with low allele burden. |